

We found a borderline negative association between road noise levels estimated with CadnaA and MI (HR: 0.99 per 10 dBA 95%CI: 0.98-1.00). The adjusted hazard ratios (HRs) (also adjusted for smoking) were 1.12 (95% Confidence Intervals : 1.08-1.15), 1.11 (95%CI: 1.07-1.14) and 1.10 (95%CI: 1.06-1.14) per 10 dBA noise levels increase respectively in Level Accoustic equivalent 24 h (LAeq24 h), Level day-evening-night (Lden) and night level (Lnight). Total noise LUR levels ranged from ~44 to ~79 dBA and varied slightly with the metric used. We found positive associations between total environmental noise, estimated by LUR models and the incidence of MI. Indirect adjustment based on ancillary data for smoking was performed.ġ,065,414 individuals were followed (total of 9,000,443 person-years) and 40,718 (3.8%) developed MI. Cox models with time-varying exposures (age as the time axis) were used to estimate the associations with various adjustments (material deprivation indicator, calendar year, nitrogen dioxide, stratification for sex). Incident MI was based on diagnostic codes in hospital admission records.

Residential noise exposure was calculated in three ways: 1) total ambient noise levels estimated by Land use regression (LUR) models 2) road traffic noise estimated by a noise propagation model CadnaA and 3) distances to transportation sources (roads, airport, railways).
CADNAA FREE
To investigate the association between long-term residential exposure to environmental/transportation noise and the incidence of myocardial infarction (MI) in the adult population living in Montreal.Īn open cohort of adults aged 45 years old and over, living on the island of Montreal and free of MI before entering the cohort was created for the years 2000-2014 with the Quebec Integrated Chronic Disease Surveillance System a systematic surveillance system from the Canadian province of Quebec starting in 1996. However, the evidence remains largely limited to the association between road traffic noise and hypertension and coronary heart diseases. Electronic address: effects of environmental noise are a growing concern. 8 School of Public Health, Centre of Public Health Research, University of Montreal and CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montreal, Canada Quebec National Institute of Public Health National, Canada.Electronic address: 1 School of Public Health, Centre of Public Health Research, University of Montreal and CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montreal, Canada.


7 Department of Civil Engineering, University of Toronto, Canada.6 Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.5 School of Public Health, Centre of Public Health Research, University of Montreal and CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montreal, Canada Quebec National Institute of Public Health National, Canada.4 Quebec National Institute of Public Health National, Canada Faculty of Pharmacy, Laval University, Canada.3 Montreal Regional Department of Public Health, Canada.2 Quebec National Institute of Public Health National, Canada.1 School of Public Health, Centre of Public Health Research, University of Montreal and CIUSSS du Centre-Sud-de-l'Île-de-Montréal, Montreal, Canada.
